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Pipeline

Development Pipeline

CandidateIndicationPreclinicalPhase 1Phase 2Phase 3
ONP-002Concussion / mTBIActive
Phase 1 Complete
Safe and well-tolerated across all dose levels; zero serious adverse events
Phase 2a Active
40-patient randomized, placebo-controlled trial underway in Australia

Platform Technology: Beyond ONP-002

While ONP-002 leads our pipeline for concussion treatment, our proprietary intranasal delivery platform has applications across multiple neurological conditions. Through our partnership with Receptor.AI, we are accelerating AI-driven exploration of additional indications.

Non-invasive
No pills, no injections — nasal spray administration
Rapid onset
Direct-to-brain delivery enables faster therapeutic action
Reduced systemic exposure
Targeted delivery minimizes side effects common with systemic drugs
Field-ready design
Portable, single-use device suitable for emergency and sports settings

Platform technology potentially applicable to:

PTSD
Stroke
Seizures
Alzheimer’s Disease
Parkinson’s Disease
Other CNS disorders
The nasal drug delivery market is projected to exceed $125 billion by 2030, with neurological applications representing one of the fastest-growing segments.

Learn More

Explore our lead asset in detail or connect with our investor relations team.